For men under 50, the more cigarettes smoked, the higher the stroke risk

Men under 50 years old who smoke are 88 percent more likely to have a stroke than men who never smoked — and the number of cigarettes a day can move that risk up or down, according to new research.

The study, in the American Heart Association’s journal Stroke, involved 1,145 men ages 15 to 49, including 615 who had had a stroke. When the numbers were broken down by cigarettes smoked, those who had fewer than 11 cigarettes a day were 46 percent more likely to have had a stroke. Men with a two-pack-a-day habit had nearly five times — or 466 percent — higher risk for a stroke than people who never smoked.

“There was a clear-cut relationship between the number of cigarettes the men were smoking and their risk for stroke,” said Janina Markidan, the study’s lead author and a third-year medical student at the University of Maryland School of Medicine. “For each subgroup, the risk went up. The more you smoke, the more you stroke.”

The study was a look at a snapshot in time and didn’t record how long the study participants had a smoking habit. But it showed that former smokers — people who had more than 100 cigarettes in their lifetime but had not smoked for the 30 days leading up to the study — had made gains. Their risk was 42 percent, less than half that of current smokers.

“There’s hope,” she said. “Our number one takeaway is the best you can do for yourself is to never smoke, but if you quit now there are benefits you will see soon after quitting. So, it’s worth it to quit, even if it’s something you’ve been doing for a long time.”

The research didn’t include information on vaping, said Dr. John Cole, a study co-author and associate professor of neurology at the University of Maryland and Baltimore Veterans Affairs Medical Center.

“But it is reasonable to consider the inhalation of a variety of chemicals through vaping to also be toxic,” he said. “I urge individuals to not vape, as the health risks associated with vaping are unknown. Further research regarding vaping and stroke risk is required.”

Smoking, of course, is commonly known as a major risk factor for cardiovascular disease. But Markidan said the study’s findings connecting the number of cigarettes to stroke risk is as important as ever. In a span of about a decade, smoking rates for men and women who have been hospitalized for stroke increased from 5 percent to 16 percent, a 2017 study found.

Cole said that while smoking is a well-established risk factor for stroke, it’s a unique one.

“It is fully under the individual’s control,” he said. “While for many individuals quitting can be challenging, they do have the ability to do so, and hence directly reduce their own stroke risk. Despite our dose-response findings, in the end, it is best to completely stop or never start in the first place.”

Read the full story from American Heart Association News.

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